Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670959 | 0.96 | MTNR1A (0.46) | MTNR1AMTNR1BATMTDP1L3MBTL1 | |
| SCHEMBL11211219 | 0.90 | MTNR1A (0.45) | MTNR1AMTNR1BATMTDP1L3MBTL1 | |
| SCHEMBL11672283 | 0.84 | MTNR1A (0.42) | MTNR1AMTNR1BATMTDP1L3MBTL1 | |
| SCHEMBL11670563 | 0.83 | MAOB (0.41) | MTNR1AMTNR1BATMTDP1L3MBTL1 | |
| SCHEMBL11670832 | 0.82 | CNR2 (0.44) | MTNR1AMTNR1BTDP1L3MBTL1 | |
| SCHEMBL9804650 | 0.82 | RAD52 (0.51) | MTNR1AMTNR1BTDP1PPARGCHRM2 | |
| SCHEMBL7375351 | 0.82 | KDM4E (0.54) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL11671287 | 0.82 | ALDH1A1 (0.43) | MTNR1AMTNR1BL3MBTL1CHRM2 | |
| SCHEMBL11672203 | 0.82 | MTNR1A (0.48) | MTNR1AMTNR1B | |
| SCHEMBL11671961 | 0.82 | LSS (0.43) | MTNR1AMTNR1BCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039526-A | PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
| US-4039539-A | 1,2,4-Triazole-azo-aniline cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |