Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597345 | 0.81 | KMT2A (0.80) | KMT2ALMNAHSD17B10HTTALDH1A1 | |
| SCHEMBL11689714 | 0.77 | KMT2A (0.80) | KMT2ALMNAHSD17B10HTTALDH1A1 | |
| SCHEMBL10985420 | 0.76 | KMT2A (0.77) | KMT2ALMNAHSD17B10HTTALDH1A1 | |
| SCHEMBL9331809 | 0.74 | KMT2A (0.67) | KMT2ALMNAHSD17B10HTTALDH1A1 | |
| SCHEMBL3742869 | 0.73 | LMNA (0.71) | KMT2ALMNAALDH1A1 | |
| SCHEMBL11069089 | 0.72 | — | — | |
| SCHEMBL9334609 | 0.72 | KMT2A (0.65) | KMT2ALMNAHSD17B10HTTALDH1A1 | |
| SCHEMBL11692007 | 0.72 | LMNA (0.64) | KMT2ALMNAHSD17B10HTTALDH1A1 | |
| SCHEMBL11335820 | 0.72 | KMT2A (0.70) | KMT2ALMNAHSD17B10HTTALDH1A1 | |
| SCHEMBL9487028 | 0.69 | KMT2A (0.59) | KMT2ALMNAHSD17B10HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064242-A | ANTIBACTERIAL AGENTS | SMITHKLINE CORPORATION (US) | 1977-12-20 | — | — | US | disclosed |