SCHEMBL4597345

SCHEMBL4597345

CSc1nnnn1CCO

nearest known ligand 0.80

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.80
LMNA P02545 1/20 0.80
CYP1A2 P05177 1/20 0.55
ALDH1A1 P00352 5/20 0.42
HTT P42858 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP2C19 P33261 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
CSNK2A1 P68400 1/20 0.35
CSNK2A3 Q8NEV1 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.34
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11689714 0.83 KMT2A (0.80) KMT2ALMNACYP1A2ALDH1A1HTT
SCHEMBL10985420 0.82 KMT2A (0.77) KMT2ALMNACYP1A2ALDH1A1HTT
SCHEMBL11670320 0.81 KMT2A (0.69) KMT2ALMNACYP1A2ALDH1A1HTT
SCHEMBL11687245 0.80 KMT2A (0.74) KMT2ALMNACYP1A2ALDH1A1HTT
SCHEMBL9331809 0.80 KMT2A (0.67) KMT2ALMNAALDH1A1HTTHSD17B10
SCHEMBL4597338 0.79 CYP1A2 (0.55) KMT2ALMNACYP1A2ALDH1A1HTT
SCHEMBL3742869 0.79 LMNA (0.71) KMT2ALMNAALDH1A1
SCHEMBL11069089 0.78
SCHEMBL9334609 0.78 KMT2A (0.65) KMT2ALMNACYP1A2ALDH1A1HTT
SCHEMBL11335820 0.78 KMT2A (0.70) KMT2ALMNACYP1A2ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004101572-A1 7-GLUTARYL IMIDE CEPHALOSPORANIC ACID DERIVATIVES AND PROCESS FOR PREPARING IT CKD BIO CORPORATION (KR) 2004-11-25 WO claimed
US-6420554-B1 REACTION OF BETA LACTAM WITH PHOSPHOROUS HALIDE IN THE PRESENCE OF BASE, ADDING PHENOL, REACTION WITH ALCOHOL AND REMOVAL OF ESTER OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2002-07-16 US claimed
EP-1010701-B1 PROCESS FOR THE PREPARATION OF 3-CEPHEM COMPOUNDS OTSUKA KAGAKU KK (JP) 2008-01-16 EP disclosed
US-6420554-B1 REACTION OF BETA LACTAM WITH PHOSPHOROUS HALIDE IN THE PRESENCE OF BASE, ADDING PHENOL, REACTION WITH ALCOHOL AND REMOVAL OF ESTER OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2002-07-16 US disclosed
EP-1010701-A1 PROCESS FOR THE PREPARATION OF 3-CEPHEM COMPOUNDS OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2000-06-21 EP disclosed
EP-1000945-A1 PROCESS FOR PRODUCING $g(b)-LACTAM DERIVATIVES OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2000-05-17 EP disclosed
EP-0289002-B1 Novel cephalosporin compounds and antibacterial agents MEIJI SEIKA KAISHA (JP) 1994-10-26 EP disclosed
EP-0315997-B1 Cephalosporin compounds and antibacterial agents MEIJI SEIKA KAISHA (JP) 1994-04-20 EP disclosed
EP-0346465-B1 1-CARBOXY-1-VYNILOXYIMINOAMINOTHIAZOLE CEPHALOSPORING DERIVATIVES AND PROCESS FOR THEIR PREPARATION BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-08-11 EP disclosed
EP-0222022-B1 PROCESS FOR PRODUCING BETA-LACTAM DERIVATIVES Otsuka Kagaku Kabushiki Kaisha (JP) 1992-09-23 EP disclosed
EP-0209751-B1 CEPHALOSPORIN DERIVATIVES AND BACTERICIDES CONTAINING THE SAME MEIJI SEIKA KAISHA LTD. (JP) 1992-09-16 EP disclosed
US-5028601-A Substituted with an amino thiazole group and a dihydroxy-pyridone group MEIJI SAIKA KAISHA, LTD. (JP) 1991-07-02 US disclosed
US-4971961-A ANTIBIOTICS AS BACTERICIDES AGAINST PSEUDOMONAS MEIJI SEIKA KAISHA, LTD. (JP) 1990-11-20 US disclosed
EP-0346465-A1 1-CARBOXY-1-VYNILOXYIMINOAMINOTHIAZOLE CEPHALOSPORING DERIVATIVES AND PROCESS FOR THEIR PREPARATION BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-12-20 EP disclosed
EP-0315997-A2 Cephalosporin compounds and antibacterial agents MEIJI SEIKA KAISHA LTD. (JP) 1989-05-17 EP disclosed
EP-0289002-A2 Novel cephalosporin compounds and antibacterial agents MEIJI SEIKA KAISHA LTD. (JP) 1988-11-02 EP disclosed
US-4758557-A Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA, LTD. (JP) 1988-07-19 US disclosed
US-4731361-A Alkeneamidocephalosporin esters SHIONOGI & CO., LTD. (JP) 1988-03-15 US disclosed
EP-0222022-A1 PROCESS FOR PRODUCING BETA-LACTAM DERIVATIVES Otsuka Kagaku Kabushiki Kaisha (JP) 1987-05-20 EP disclosed
EP-0209751-A2 Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA LTD. (JP) 1987-01-28 EP disclosed