Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.73 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.71 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.60 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.60 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | NT5E | P21589 | 2/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.47 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6346835 | 1.00 | APEX1 (0.73) | APEX1ENPP2SUMO2SUMO1SENP7 | |
| SCHEMBL11670965 | 1.00 | APEX1 (0.73) | APEX1ENPP2SUMO2SUMO1SENP7 | |
| SCHEMBL11670471 | 0.99 | APEX1 (0.72) | APEX1ENPP2SUMO2SUMO1SENP7 | |
| SCHEMBL11849783 | 0.91 | APEX1 (0.60) | APEX1ENPP2SUMO2SUMO1SENP7 | |
| SCHEMBL11849768 | 0.91 | APEX1 (0.60) | APEX1ENPP2SUMO2SUMO1SENP7 | |
| SCHEMBL13763516 | 0.89 | ENPP2 (0.69) | APEX1ENPP2SUMO2SUMO1SENP7 | |
| SCHEMBL11226640 | 0.87 | ENPP2 (0.67) | APEX1ENPP2SUMO2SUMO1SENP7 | |
| SCHEMBL11226638 | 0.87 | ENPP2 (0.67) | APEX1ENPP2SUMO2SUMO1SENP7 | |
| SCHEMBL11760582 | 0.87 | APEX1 (0.61) | APEX1ENPP2SUMO2SUMO1SENP7 | |
| SCHEMBL11760573 | 0.87 | APEX1 (0.61) | APEX1ENPP2SUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061627-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |