Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21515192 | 0.84 | AR (0.34) | AR | |
| SCHEMBL2743640 | 0.78 | MAPT (0.36) | — | |
| SCHEMBL11671275 | 0.73 | KDM4E (0.31) | KDM4EL3MBTL1 | |
| SCHEMBL11670927 | 0.72 | KDM4E (0.54) | KDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL15149654 | 0.70 | KDM4E (0.50) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL10465159 | 0.69 | L3MBTL1 (0.50) | KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11671025 | 0.69 | MAPK1 (0.48) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL2760434 | 0.68 | CYP2A6 (0.48) | KDM4EALDH1A1HPGDL3MBTL1AR | |
| SCHEMBL7289270 | 0.68 | ESR1 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL6321020 | 0.68 | HTT (0.35) | ALDH1A1HPGDHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4036965-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |