Toluene

Toluene

SCHEMBL11670677

C=C(C)c1ccccc1.Cc1ccccc1

nearest known ligand 0.84

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.58
TSHR P16473 1/20 0.58
ALOX12 P18054 1/20 0.58
ACHE P22303 1/20 0.58
CES2 O00748 2/20 0.50
CES1 P23141 2/20 0.50
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 4/20 0.42
MAPT P10636 4/20 0.42
HPGD P15428 2/20 0.42
POLB P06746 2/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
XBP1 P17861 1/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALDH1A1 P00352 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL27553718 0.97 LMNA (0.55) LMNATSHRALOX12ACHECES2
SCHEMBL3267692 0.92 CES2 (0.48) LMNATSHRALOX12ACHECES2
SCHEMBL6577 0.92
Hydrogen Peroxide SCHEMBL7249472 0.92 CES2 (0.48) LMNATSHRALOX12ACHECES2
SCHEMBL2905282 0.92
Benzene SCHEMBL28197619 0.92 CES2 (0.48) LMNATSHRALOX12ACHECES2
SCHEMBL1331472 0.92
SCHEMBL472891 0.92 CES2 (0.48) LMNATSHRALOX12ACHECES2
Ethylene SCHEMBL3701342 0.89 CES2 (0.46) LMNATSHRALOX12ACHECES2
SCHEMBL11701025 0.89 CES2 (0.46) LMNATSHRALOX12ACHECES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115678596-A Method for removing alkadiene by selective hydrogenation of light hydrocarbon 中国石油大学(华东) 2023-02-03 CN disclosed
US-4020228-A Gel composition, heat sealable substrates, and process for heat sealing W. R. GRACE & CO. (US) 1977-04-26 US disclosed