Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 5/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464521 | 0.93 | ADRB2 (0.46) | NR1H3HCRTR2MEN1KMT2AADRB2 | |
| SCHEMBL11670459 | 0.85 | MEN1 (0.38) | NR1H3MEN1KMT2ATRPM8 | |
| SCHEMBL11670137 | 0.84 | MEN1 (0.38) | NR1H3HCRTR2MEN1KMT2AADRB3 | |
| SCHEMBL11748916 | 0.84 | ELANE (0.40) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL11670452 | 0.81 | MEN1 (0.39) | NR1H3MEN1KMT2ATRPM8 | |
| SCHEMBL10464981 | 0.80 | ADRB2 (0.43) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL10465029 | 0.78 | ADRB2 (0.40) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL10465045 | 0.78 | ADRB2 (0.42) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL11571707 | 0.78 | MEN1 (0.40) | NR1H3MEN1KMT2ATRPM8ADRB2 | |
| SCHEMBL3070143 | 0.76 | APP (0.40) | MEN1KMT2AADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024281-A | N,N-bis[2-(3-substituted-4-hydroxyphenyl)-ethyl or -2-hydroxyethyl]-polymethylenediamines | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |