Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.36 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.36 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465029 | 0.93 | ADRB2 (0.40) | MEN1KMT2AKCNH2ADRB3HTR7 | |
| SCHEMBL11670700 | 0.84 | NR1H3 (0.40) | MEN1KMT2AADRB3NR1H3HCRTR2 | |
| SCHEMBL11748916 | 0.83 | ELANE (0.40) | MEN1KMT2AALDH1A1PRMT5WDR77 | |
| SCHEMBL11670459 | 0.83 | MEN1 (0.38) | MEN1KMT2ACCR5NR1H3 | |
| SCHEMBL10464981 | 0.79 | ADRB2 (0.43) | MEN1KMT2AKCNH2ALDH1A1RAB9A | |
| SCHEMBL11670452 | 0.78 | MEN1 (0.39) | MEN1KMT2APRMT5WDR77NR1H3 | |
| SCHEMBL10464521 | 0.78 | ADRB2 (0.46) | MEN1KMT2AKCNH2ALDH1A1RAB9A | |
| SCHEMBL6074837 | 0.78 | ADRB3 (0.50) | ADRB3 | |
| SCHEMBL7086395 | 0.77 | KMT2A (0.38) | MEN1KMT2ACCR5LMNAACP1 | |
| SCHEMBL10463996 | 0.76 | MEN1 (0.43) | MEN1KMT2ACCR5ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024281-A | N,N-bis[2-(3-substituted-4-hydroxyphenyl)-ethyl or -2-hydroxyethyl]-polymethylenediamines | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3933913-A | N,N'-bis[3-substituted-4-hydroxypheyl)-2-hydroxyethyl)]-polymethylenediamines | SMITHKLINE CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |