SCHEMBL11670972

SCHEMBL11670972

CCN(c1cccc(C)c1C)C(C)OC(=O)Oc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TSHR P16473 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MAPK1 P28482 1/20 0.37
LMNA P02545 2/20 0.36
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
MTNR1A P48039 3/20 0.35
MTNR1B P49286 3/20 0.35
CYP3A4 P08684 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
RXRA P19793 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
FAAH O00519 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11671374 0.91 CYP3A4 (0.38) ALDH1A1TSHRLMNAMAPTTDP1
SCHEMBL11678038 0.82 MAPK1 (0.35) ALDH1A1TSHRSMN1; SMN2MAPK1LMNA
SCHEMBL11671662 0.81 TSPO (0.47) LMNAMAPT
SCHEMBL11671865 0.81 ESR1 (0.39) TSHRSMN1; SMN2MTNR1AMTNR1BMEN1
SCHEMBL11671701 0.80 TDP1 (0.42) ALDH1A1TSHRSMN1; SMN2LMNAMAPT
SCHEMBL11699625 0.80 MTNR1A (0.37) TSHRLMNATDP1MTNR1AMTNR1B
SCHEMBL11671571 0.80 HSD17B10 (0.45) ALDH1A1TSHRSMN1; SMN2MAPK1LMNA
Hydrochloric Acid SCHEMBL11671225 0.79 TDP1 (0.41) ALDH1A1TSHRSMN1; SMN2LMNAMAPT
SCHEMBL11670389 0.78 POLB (0.39) ALDH1A1TSHRMAPK1LMNAMAPT
SCHEMBL11671871 0.78 MAPT (0.42) ALDH1A1MAPK1LMNAMAPTMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4039526-A PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-08-02 US disclosed
US-4039539-A 1,2,4-Triazole-azo-aniline cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-08-02 US disclosed