Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CD40 | P25942 | 1/20 | 0.48 |
| ▸ | CD40LG | P29965 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 10/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671754 | 1.00 | THRB (0.50) | THRBMEN1KMT2ATDP1CD40 | |
| SCHEMBL11671548 | 0.92 | MEN1 (0.60) | THRBMEN1KMT2ATDP1CD40 | |
| SCHEMBL11671554 | 0.92 | MEN1 (0.60) | THRBMEN1KMT2ATDP1CD40 | |
| SCHEMBL11672215 | 0.91 | CYP1A2 (0.47) | THRBMEN1KMT2ATDP1CD40 | |
| SCHEMBL11672209 | 0.91 | CYP1A2 (0.47) | THRBMEN1KMT2ATDP1CD40 | |
| SCHEMBL13880657 | 0.90 | ENPP2 (0.55) | THRBMEN1KMT2ATDP1CD40 | |
| SCHEMBL13880680 | 0.89 | CD40 (0.49) | THRBMEN1KMT2ATDP1CD40 | |
| SCHEMBL13880629 | 0.89 | ENPP2 (0.55) | THRBMEN1KMT2ATDP1CD40 | |
| SCHEMBL11671910 | 0.88 | CD40 (0.47) | THRBMEN1KMT2ATDP1CD40 | |
| SCHEMBL11671907 | 0.88 | CD40 (0.47) | THRBMEN1KMT2ATDP1CD40 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029598-A | AZO DYES HAVING A SULFONIC ACID OR CARBOXYL GROUP | E. MERCK A. G. (DT) | 1977-06-14 | — | — | US | claimed |