Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | EBP | Q15125 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benderizine SCHEMBL1816506 | 1.00 | ALDH1A1 (0.47) | ALDH1A1GAATDP1KMT2APOLB | |
| Benderizine SCHEMBL11673215 | 0.99 | ALDH1A1 (0.46) | ALDH1A1GAATDP1KMT2APOLB | |
| SCHEMBL11628159 | 0.94 | ACHE (0.43) | ALDH1A1GAATDP1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL11630062 | 0.93 | ACHE (0.42) | ALDH1A1GAATDP1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL11672394 | 0.93 | RECQL (0.47) | ALDH1A1GAATDP1KMT2AMEN1 | |
| Benderizine SCHEMBL11673362 | 0.92 | ALDH1A1 (0.43) | ALDH1A1GAATDP1KMT2APOLB | |
| SCHEMBL11630816 | 0.90 | GAA (0.44) | ALDH1A1GAATDP1KMT2AMEN1 | |
| SCHEMBL11630162 | 0.90 | ALDH1A1 (0.42) | ALDH1A1GAATDP1KMT2AMEN1 | |
| SCHEMBL11628858 | 0.89 | ACHE (0.46) | ALDH1A1GAATDP1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL11630911 | 0.88 | ACHE (0.45) | KMT2APOLBMEN1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3996360-A | ANTIARRHYTHMIA | KNOLL A.G. CHEMISCHE FABRIKEN (DT) | 1976-12-07 | — | — | US | claimed |
| US-4031216-A | CARDIAC DISEASE, ARRHYTHMIA | KNOLL A.G. CHEMISCHE FABRIKEN (DT) | 1977-06-21 | — | — | US | disclosed |
| US-3996360-A | ANTIARRHYTHMIA | KNOLL A.G. CHEMISCHE FABRIKEN (DT) | 1976-12-07 | — | — | US | disclosed |