Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11674319 | 1.00 | PLCG1 (0.81) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL8766580 | 0.91 | PLCG1 (0.83) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL28528206 | 0.91 | PLCG1 (0.83) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL8766584 | 0.91 | PLCG1 (0.83) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL7771463 | 0.90 | PLCG1 (0.67) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL10779487 | 0.90 | PLCG1 (0.67) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11130980 | 0.90 | PLCG1 (0.67) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL9152111 | 0.90 | PLCG1 (0.67) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL10412277 | 0.90 | PLCG1 (1.00) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11512916 | 0.90 | PLCG1 (0.81) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065621-A | Process for 3-alkyl and 3-phenyl cephalosporins | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4065618-A | Process for 3-H-3-cephem esters | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4013651-A | 3-SUBSTITUTED AMINO-CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1977-03-22 | — | — | US | disclosed |