Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SPOP | O43791 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152111 | 1.00 | PLCG1 (0.67) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL10779487 | 1.00 | PLCG1 (0.67) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL11130980 | 1.00 | PLCG1 (0.67) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL10840113 | 0.91 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL27938962 | 0.91 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL10820995 | 0.91 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL8533433 | 0.91 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL1010087 | 0.91 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL11690202 | 0.91 | PLCG1 (0.65) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL11686985 | 0.91 | PLCG1 (0.65) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334590-B1 | 3-(Substituted)-1-carba(dethia)-3-cephems and cephalosporins and a process for production therefor | LILLY CO ELI (US) | 2001-07-04 | — | — | EP | disclosed |
| EP-0677523-A1 | 3-(substituted)-1-carba(dethia)-3-cephems and cephalosporins and a process for production therefor | ELI LILLY AND COMPANY (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0334592-B1 | A process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia)cephalosporins | LILLY CO ELI (US) | 1995-01-25 | — | — | EP | disclosed |
| US-5128336-A | Antibiotics | ELI LILLY AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0334590-A2 | 3-(Substituted)-1-carba(dethia)-3-cephems and cephalosporins and a process for production therefor | ELI LILLY AND COMPANY (US) | 1989-09-27 | — | — | EP | disclosed |
| EP-0334592-A2 | A process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia)cephalosporins | ELI LILLY AND COMPANY (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4855418-A | Process for production of ceophalosporins | ELI LILLY AND COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| US-4820832-A | Process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia)cephalosporins | ELI LILLY AND COMPANY (US) | 1989-04-11 | — | — | US | disclosed |