Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PDE2A | O00408 | 1/20 | 0.55 |
| ▸ | PDE5A | O76074 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.55 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.55 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11133671 | 0.86 | ALDH1A1 (0.54) | ALDH1A1KMT2ACYP3A4MEN1POLB | |
| SCHEMBL2960533 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KMT2ACYP3A4MEN1POLB | |
| SCHEMBL6935992 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KMT2ACYP3A4MEN1POLB | |
| SCHEMBL11444918 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KMT2ACYP3A4MEN1POLB | |
| SCHEMBL11021422 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KMT2ACYP3A4MEN1POLB | |
| SCHEMBL5901610 | 0.77 | ALDH1A1 (0.71) | ALDH1A1KMT2ACYP3A4MEN1POLB | |
| SCHEMBL266593 | 0.75 | ALDH1A1 (0.76) | ALDH1A1KMT2ACYP3A4MEN1POLB | |
| SCHEMBL11676296 | 0.75 | POLB (0.49) | ALDH1A1CYP3A4POLBLMNAGPR35 | |
| SCHEMBL10876154 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KMT2ACYP3A4MEN1POLB | |
| SCHEMBL5901748 | 0.73 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060544-A | COUPLERS | GAF CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |
| US-4039524-A | Keto-amido containing phenylazo benzothiazole dyestuffs | GAF CORPORATION (US) | 1977-08-02 | — | — | US | disclosed |
| US-3931145-A | POLYESTER | GAF CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |