Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11444918 | 0.84 | ALDH1A1 (0.51) | POLBHTTVCAM1ALDH1A1CYP3A4 | |
| SCHEMBL11451900 | 0.79 | S1PR4 (0.53) | POLBHTTVCAM1ALDH1A1CYP3A4 | |
| SCHEMBL2960533 | 0.79 | ALDH1A1 (0.56) | POLBHTTVCAM1ALDH1A1CYP3A4 | |
| SCHEMBL22408944 | 0.75 | ALDH1A1 (0.47) | VCAM1ALDH1A1CYP3A4LMNACYP19A1 | |
| SCHEMBL6935992 | 0.75 | ALDH1A1 (0.56) | POLBHTTALDH1A1CYP3A4LMNA | |
| SCHEMBL7033848 | 0.75 | HTT (0.79) | POLBHTTALDH1A1CYP3A4LMNA | |
| SCHEMBL11676104 | 0.75 | ALDH1A1 (0.55) | POLBHTTVCAM1ALDH1A1CYP3A4 | |
| SCHEMBL10882778 | 0.74 | VCAM1 (0.69) | POLBHTTVCAM1ALDH1A1CYP3A4 | |
| SCHEMBL31022516 | 0.73 | VCAM1 (0.57) | POLBHTTVCAM1ALDH1A1LMNA | |
| SCHEMBL11440304 | 0.72 | ALDH1A1 (0.49) | POLBHTTALDH1A1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060544-A | COUPLERS | GAF CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |
| US-4039524-A | Keto-amido containing phenylazo benzothiazole dyestuffs | GAF CORPORATION (US) | 1977-08-02 | — | — | US | disclosed |
| US-3931145-A | POLYESTER | GAF CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |