Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11676473 | 1.00 | NAAA (0.61) | NAAATDP1POLBMEN1KMT2A | |
| SCHEMBL27623142 | 1.00 | NAAA (0.61) | NAAATDP1POLBMEN1KMT2A | |
| SCHEMBL27530408 | 0.94 | POLB (0.66) | NAAATDP1POLBMEN1KMT2A | |
| SCHEMBL11675750 | 0.92 | TDP1 (0.59) | NAAATDP1POLBMEN1KMT2A | |
| SCHEMBL11677909 | 0.86 | MEN1 (0.79) | TDP1POLBMEN1KMT2ANPC1 | |
| SCHEMBL11675778 | 0.86 | NAAA (0.67) | NAAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8063746 | 0.85 | NAAA (0.69) | NAAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11678436 | 0.85 | NAAA (0.69) | NAAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL23969603 | 0.84 | POLB (0.68) | TDP1POLBMEN1KMT2ATSHR | |
| SCHEMBL11677530 | 0.82 | ALDH1A1 (0.60) | TDP1POLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016287-A | COSMETIC AND ANTIINFLAMMATORY | BOEHRINGER INGELHEIM GMBH (DT) | 1977-04-05 | — | — | US | disclosed |