Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681462 | 0.83 | LMNA (0.51) | LMNAPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL11681313 | 0.82 | LMNA (0.50) | LMNAPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL10615262 | 0.81 | LMNA (0.60) | LMNAPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL9424254 | 0.80 | LMNA (0.74) | LMNAPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL4750857 | 0.78 | LMNA (0.72) | LMNAPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL6729463 | 0.78 | LMNA (0.64) | LMNAPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL10816709 | 0.78 | LMNA (0.72) | LMNAPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL11311097 | 0.77 | LMNA (0.67) | LMNAPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL10871534 | 0.77 | LMNA (0.67) | LMNAPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL6734172 | 0.77 | LMNA (0.63) | LMNAPOLBMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013774-A | INSECTICIDAL N-THIO-SUBSTITUTED CARBAMATES OF DIHYDROBENZOFURANOLS | CHEVRON RESEARCH COMPANY (US) | 1977-03-22 | — | — | US | disclosed |