Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677467 | 0.96 | KDM4E (0.56) | KDM4EL3MBTL1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL11679282 | 0.82 | KDM4E (0.65) | KDM4EL3MBTL1MCHR1DRD3MEN1 | |
| SCHEMBL11680146 | 0.81 | KDM4E (0.88) | KDM4EL3MBTL1ALDH1A1MCHR1MAPT | |
| Hydrochloric Acid SCHEMBL11678795 | 0.80 | KDM4E (0.86) | KDM4EL3MBTL1ALDH1A1MCHR1MAPT | |
| SCHEMBL11677379 | 0.80 | KDM4E (0.86) | KDM4EL3MBTL1ALDH1A1MCHR1MAPT | |
| SCHEMBL11678838 | 0.79 | L3MBTL1 (0.68) | KDM4EL3MBTL1ALDH1A1NPC1MAPT | |
| SCHEMBL11678065 | 0.78 | KMT2A (0.67) | KDM4EL3MBTL1MCHR1DRD3MEN1 | |
| SCHEMBL11677718 | 0.78 | KDM4E (0.79) | KDM4EL3MBTL1ALDH1A1MCHR1NPC1 | |
| SCHEMBL11676917 | 0.77 | KDM4E (0.65) | KDM4EL3MBTL1ALDH1A1MCHR1NPC1 | |
| SCHEMBL11679191 | 0.77 | KDM4E (0.81) | KDM4EL3MBTL1ALDH1A1MCHR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |