Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 12/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678065 | 0.96 | KMT2A (0.67) | KDM4EL3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL11863515 | 0.87 | KMT2A (0.58) | KDM4EL3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL11680146 | 0.84 | KDM4E (0.88) | KDM4EL3MBTL1KMT2AHTR1ADRD3 | |
| SCHEMBL11677379 | 0.83 | KDM4E (0.86) | KDM4EL3MBTL1KMT2AHTR1ADRD3 | |
| Hydrochloric Acid SCHEMBL11678795 | 0.83 | KDM4E (0.86) | KDM4EL3MBTL1KMT2AMEN1MCHR1 | |
| SCHEMBL11797618 | 0.83 | KMT2A (0.62) | KDM4EL3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL11676917 | 0.83 | KDM4E (0.65) | KDM4EL3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL11678851 | 0.82 | KMT2A (0.65) | KDM4EL3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL11678838 | 0.82 | L3MBTL1 (0.68) | KDM4EL3MBTL1KMT2ADRD3HTR7 | |
| SCHEMBL11677726 | 0.82 | KDM4E (0.61) | KDM4EL3MBTL1KMT2AMEN1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |