SCHEMBL11678596

SCHEMBL11678596

Cc1cccc(C=O)c1OCl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TSHR P16473 1/20 0.54
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
LMNA P02545 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
BLM P54132 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TRIM24 O15164 2/20 0.41
TRIM33 Q9UPN9 2/20 0.41
SRC P12931 1/20 0.40
ERN1 O75460 3/20 0.39
TLR2 O60603 1/20 0.39
TLR1 Q15399 1/20 0.39
TLR6 Q9Y2C9 1/20 0.39
NPSR1 Q6W5P4 1/20 0.36
HPGD P15428 2/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1597634 0.82 CA1 (0.63) ALDH1A1TSHRCA1CA2LMNA
SCHEMBL15183447 0.80 ALDH1A1 (0.54) ALDH1A1TSHRCA1CA2LMNA
SCHEMBL3288767 0.78 CYP1A2 (0.43) ALDH1A1TSHRCA1CA2LMNA
SCHEMBL4195713 0.78 KMT2A (0.46) ALDH1A1TSHRCA1CA2LMNA
SCHEMBL1598490 0.77 TSHR (0.50) ALDH1A1TSHRCA1CA2LMNA
SCHEMBL1253501 0.77 ALDH1A1 (0.50) ALDH1A1TSHRCA1CA2LMNA
SCHEMBL18124516 0.76 TSHR (0.48) ALDH1A1TSHRCA1CA2LMNA
SCHEMBL3432512 0.76 ALDH1A1 (0.48) ALDH1A1TSHRCA1CA2TRIM24
SCHEMBL4746689 0.75 PTGDR2 (0.57) ALDH1A1TSHRCA1CA2LMNA
SCHEMBL8211262 0.74 ALDH1A1 (0.38) ALDH1A1TSHRCA1CA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4019857-A Process for the coloration of hydrophobic chemical fibers by metalliferous dyestuffs of cationic character PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-04-26 US disclosed