Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11678799 | 0.98 | RAB9A (0.51) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL2938985 | 0.83 | RAB9A (0.58) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL11677470 | 0.83 | RAB9A (0.53) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL11678805 | 0.81 | L3MBTL1 (0.54) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL10008853 | 0.81 | HSD17B3 (0.57) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11865927 | 0.81 | MAPK1 (0.41) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL4583779 | 0.80 | HSD17B3 (0.58) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL21610337 | 0.80 | HSD17B3 (0.58) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL11780746 | 0.79 | NPC1 (0.53) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL1114930 | 0.79 | RAB9A (0.56) | RAB9ANPC1MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |