Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 10/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678344 | 0.83 | SIGMAR1 (0.40) | DRD4KDM1AHTR2AHRH1SLC6A2 | |
| SCHEMBL11680405 | 0.83 | DRD2 (0.37) | DRD4KDM1AHTR2AHRH1SLC6A2 | |
| SCHEMBL11678485 | 0.82 | DRD4 (0.56) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11680751 | 0.79 | SIGMAR1 (0.43) | DRD4KDM1ASLC6A2 | |
| SCHEMBL11678062 | 0.76 | DRD4 (0.52) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11682308 | 0.74 | PPIB (0.38) | KDM1ASLC6A2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11679347 | 0.71 | SLC6A2 (0.43) | DRD4HTR2AHRH1SLC6A2HTR2C | |
| SCHEMBL11677994 | 0.70 | SLC6A2 (0.49) | HTR2AHRH1SLC6A2CYP2D6 | |
| SCHEMBL11681058 | 0.67 | KCNH2 (0.42) | DRD4KDM1AHTR2AHRH1SLC6A2 | |
| SCHEMBL11678636 | 0.67 | HRH3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017621-A | 2-Morpholinyl tricyclic dibenzazepine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-04-12 | — | — | US | disclosed |