Orthocresol

Orthocresol

SCHEMBL11679129

Cc1cccc(O)c1C.Cc1cccc(O)c1C.Cc1ccccc1O.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.71
ATM Q13315 1/20 0.71
CYP2C19 P33261 2/20 0.58
CYP1A2 P05177 1/20 0.58
CA12 O43570 2/20 0.46
CA2 P00918 2/20 0.46
CA3 P07451 2/20 0.46
CA4 P22748 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA1 P00915 1/20 0.46
GLA P06280 1/20 0.46
CA9 Q16790 1/20 0.46
HSD17B10 Q99714 3/20 0.42
TP53 P04637 2/20 0.42
MAPT P10636 2/20 0.42
GAA P10253 1/20 0.42
MAPK1 P28482 1/20 0.42
NPC1 O15118 2/20 0.41
LMNA P02545 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orthocresol SCHEMBL11030781 1.00 TRPA1 (0.71) TRPA1ATMCYP2C19CYP1A2CA12
Orthocresol SCHEMBL11213183 1.00 TRPA1 (0.71) TRPA1ATMCYP2C19CYP1A2CA12
Orthocresol SCHEMBL11678278 1.00 TRPA1 (0.71) TRPA1ATMCYP2C19CYP1A2CA12
Phenol SCHEMBL11792275 0.96 TRPA1 (0.77) TRPA1ATMCYP2C19CYP1A2CA12
Phenol SCHEMBL1471734 0.96 TRPA1 (0.77) TRPA1ATMCYP2C19CYP1A2CA12
Orthocresol SCHEMBL8664909 0.91 TRPA1 (0.85) TRPA1ATMCYP2C19CYP1A2CA12
Orthocresol SCHEMBL3064108 0.91 TRPA1 (0.85) TRPA1ATMCYP2C19CYP1A2CA12
Orthocresol SCHEMBL9404100 0.91 TRPA1 (0.85) TRPA1ATMCYP2C19CYP1A2CA12
P-Cresol SCHEMBL11104677 0.91 CYP1A2 (0.68) TRPA1ATMCYP2C19CYP1A2CA12
Phenol SCHEMBL6131043 0.90 TRPA1 (0.68) TRPA1ATMCYP2C19CYP1A2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4024195-A CATALYST, ALCOHOL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-05-17 US disclosed