Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677994 | 0.87 | SLC6A2 (0.49) | HTR1ASLC6A2SLC6A3SLC6A4ADRB2 | |
| SCHEMBL11678744 | 0.84 | SLC6A2 (0.42) | HTR1ASLC6A2SLC6A3SLC6A4ADRB2 | |
| SCHEMBL11679397 | 0.82 | GRIN1 (0.44) | GRIN1GRIN2BHTR1ASLC6A2SLC6A3 | |
| SCHEMBL11679216 | 0.82 | SLC6A2 (0.48) | HTR1ASLC6A2SLC6A3SLC6A4ADRB2 | |
| SCHEMBL11679775 | 0.81 | GRIN1 (0.43) | GRIN1GRIN2BHTR1ASLC6A2SLC6A3 | |
| SCHEMBL7832589 | 0.72 | SLC6A2 (0.51) | HTR1ASLC6A2SLC6A3SLC6A4ADRB2 | |
| SCHEMBL11679858 | 0.70 | SLC6A2 (0.51) | HTR1ASLC6A2SLC6A3SLC6A4ADRB2 | |
| SCHEMBL1552540 | 0.68 | HTR1A (0.58) | GRIN1GRIN2BHTR1ASLC6A2SLC6A4 | |
| SCHEMBL1551841 | 0.68 | HTR1A (0.58) | GRIN1GRIN2BHTR1ASLC6A2SLC6A4 | |
| SCHEMBL1551857 | 0.68 | HTR1A (0.58) | GRIN1GRIN2BHTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017621-A | 2-Morpholinyl tricyclic dibenzazepine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-04-12 | — | — | US | disclosed |