Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 20/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11683386 | 0.84 | SLC6A2 (0.45) | DRD4CYP1A2CYP3A4CYP2D6DRD2 | |
| SCHEMBL11680286 | 0.83 | DRD4 (0.54) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11678062 | 0.82 | DRD4 (0.52) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11680001 | 0.78 | DRD4 (0.59) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11681058 | 0.77 | KCNH2 (0.42) | DRD4CYP3A4DRD2DRD3 | |
| SCHEMBL11680933 | 0.76 | DRD2 (0.39) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11680046 | 0.76 | SLC6A2 (0.43) | — | |
| SCHEMBL11678485 | 0.76 | DRD4 (0.56) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11681955 | 0.75 | DRD2 (0.53) | DRD4CYP3A4DRD2DRD3 | |
| SCHEMBL11681427 | 0.74 | DRD4 (0.39) | DRD4CYP3A4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017621-A | 2-Morpholinyl tricyclic dibenzazepine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-04-12 | — | — | US | disclosed |