Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | JAK1 | P23458 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | CAMK1D | Q8IU85 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | FLT4 | P35916 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678123 | 0.98 | ABL1 (0.37) | ABL1JAK2JAK1JAK3PSMB8 | |
| SCHEMBL11678400 | 0.86 | KMO (0.39) | ABL1JAK2JAK1JAK3PSMB8 | |
| SCHEMBL11684120 | 0.85 | KMO (0.41) | ABL1JAK2JAK1JAK3PSMB8 | |
| SCHEMBL11678789 | 0.80 | CSNK1D (0.37) | JAK2JAK1JAK3PSMB8PSMB9 | |
| SCHEMBL11678968 | 0.79 | ALDH1A1 (0.38) | ABL1JAK2JAK1JAK3PSMB8 | |
| SCHEMBL29457441 | 0.78 | KDM4E (0.50) | ABL1KDM4EGLAHTTKMT2A | |
| SCHEMBL11681475 | 0.78 | JAK2 (0.34) | ABL1JAK2JAK1JAK3PSMB8 | |
| SCHEMBL11678971 | 0.77 | PSMB8 (0.36) | ABL1JAK2JAK1JAK3PSMB8 | |
| SCHEMBL1847827 | 0.75 | NPC1 (0.36) | EPHX1FLT4KDM4ESMN1; SMN2TDP1 | |
| SCHEMBL29457355 | 0.75 | KDM4E (0.47) | ABL1GLSKDM4EGLAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046763-A | INTERMEDIATE FOR ULTRAVIOLET LIGHT ABSORBERS | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-06 | — | — | US | disclosed |