Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.65 |
| ▸ | PGR | P06401 | 7/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682401 | 0.95 | CYP3A4 (0.65) | CYP3A4PGRNR3C1ABCB11LMNA | |
| SCHEMBL11685819 | 0.94 | PGR (0.66) | CYP3A4PGRNR3C1ABCB11LMNA | |
| SCHEMBL11685946 | 0.92 | CYP3A4 (0.64) | CYP3A4PGRNR3C1ABCB11LMNA | |
| SCHEMBL11682152 | 0.91 | PGR (0.79) | CYP3A4PGRNR3C1ABCB11LMNA | |
| SCHEMBL11681125 | 0.87 | PGR (0.78) | CYP3A4PGRNR3C1ABCB11LMNA | |
| SCHEMBL11683876 | 0.87 | PGR (0.78) | CYP3A4PGRNR3C1ABCB11LMNA | |
| SCHEMBL11684827 | 0.85 | PGR (0.78) | CYP3A4PGRNR3C1ABCB11LMNA | |
| SCHEMBL11682785 | 0.85 | PGR (0.78) | CYP3A4PGRNR3C1ABCB11LMNA | |
| SCHEMBL11682409 | 0.84 | NR3C1 (0.77) | CYP3A4PGRNR3C1ABCB11LMNA | |
| SCHEMBL11680892 | 0.84 | PGR (0.75) | CYP3A4PGRNR3C1ABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065452-A | TOPICAL ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-12-27 | — | — | US | disclosed |