Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682130 | 0.86 | GABRA1 (0.32) | GABRA1GABRB2ALOX15ALOX12 | |
| SCHEMBL11683274 | 0.84 | — | — | |
| SCHEMBL6419844 | 0.83 | ALOX5 (0.36) | GABRA1GABRB2PTPN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9196936 | 0.81 | GABRA1 (0.48) | GABRA1GABRB2PTPN1ALDH1A1ALOX15 | |
| SCHEMBL9325758 | 0.81 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1POLB | |
| SCHEMBL8342795 | 0.79 | GABRA1 (0.54) | GABRA1GABRB2ALDH1A1POLBMAPK1 | |
| SCHEMBL1538588 | 0.78 | GABRA1 (0.61) | GABRA1GABRB2GPR84ALDH1A1POLB | |
| SCHEMBL4057921 | 0.77 | GABRA1 (0.56) | GABRA1GABRB2PTPN1ALDH1A1POLB | |
| SCHEMBL17187961 | 0.76 | GABRA1 (0.60) | GABRA1GABRB2PTPN1GPR84ALOX15 | |
| SCHEMBL16182674 | 0.76 | GABRA1 (0.50) | GABRA1GABRB2MAPK1ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038327-A | ANTIOXIDANTS FOR POLYOLEFINS | THE QUAKER OATS COMPANY (US) | 1977-07-26 | — | — | US | disclosed |