Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | TPMT | P51580 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679767 | 0.86 | TSHR (0.50) | TTRALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL31214608 | 0.78 | TTR (0.65) | TTRALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL11677598 | 0.78 | TSHR (0.54) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL9088276 | 0.76 | PLA2G2D (0.47) | TTRALDH1A1KDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9812943 | 0.76 | TSHR (0.52) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL9623558 | 0.75 | AKR1C2 (0.47) | TTRALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL945628 | 0.75 | PTPN1 (0.59) | TTRALDH1A1KDM4EMEN1HPGD | |
| Hydrochloric Acid SCHEMBL10957441 | 0.74 | PTPN1 (0.57) | TTRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3769878 | 0.72 | TTR (0.58) | TTRALDH1A1TSHRCASP1SMN1; SMN2 | |
| SCHEMBL30162746 | 0.72 | TSHR (0.68) | TTRALDH1A1KDM4EMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042571-A | Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant | TEIJIN LIMITED (JA) | 1977-08-16 | — | — | US | claimed |