SCHEMBL9623558

SCHEMBL9623558

O=C(O)c1ccc2c(Cl)c(O)c(Cl)cc2c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C2 P52895 6/20 0.47
AKR1C1 Q04828 6/20 0.47
AKR1C4 P17516 1/20 0.47
AKR1C3 P42330 1/20 0.47
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 3/20 0.46
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
HPGD P15428 2/20 0.46
MAPT P10636 1/20 0.46
PKM P14618 1/20 0.46
HTT P42858 1/20 0.46
TSHR P16473 4/20 0.44
CASP1 P29466 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TTR P02766 2/20 0.42
TP53 P04637 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
CA1 P00915 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11677598 0.82 TSHR (0.54) ALDH1A1HSD17B10KDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL9812943 0.80 TSHR (0.52) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL9623621 0.77 CA1 (0.48) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL4069345 0.77 DPP4 (0.56) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL9623619 0.76 HSD17B10 (0.60) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL11680717 0.75 TTR (0.47) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL1513825 0.72 AKR1C2 (0.63) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL14273026 0.72 AKR1C2 (0.57) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL18529852 0.72 SELL (0.56) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL4124483 0.71 TSHR (0.50) ALDH1A1HSD17B10KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed