SCHEMBL3769878

SCHEMBL3769878

O=C(O)c1cc(Cl)c(Cl)c(C(=O)O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.58
TSHR P16473 4/20 0.50
TPMT P51580 2/20 0.50
CYP3A4 P08684 1/20 0.45
SRD5A2 P31213 1/20 0.44
ALDH1A1 P00352 3/20 0.43
TP53 P04637 1/20 0.43
CASP1 P29466 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HCAR1 Q9BXC0 1/20 0.43
DAO P14920 1/20 0.43
PLAU P00749 1/20 0.43
GPR35 Q9HC97 1/20 0.42
AKR1C4 P17516 1/20 0.42
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
AKR1C1 Q04828 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11257407 0.88 TPMT (0.56) TTRTSHRTPMTCYP3A4ALDH1A1
SCHEMBL7263572 0.85 TTR (0.68) TTRTSHRTPMTCYP3A4SRD5A2
Fluoride SCHEMBL27668632 0.83 TTR (0.65) TTRTSHRTPMTCYP3A4SRD5A2
SCHEMBL27214470 0.81 ALDH1A1 (0.46) TTRTSHRTPMTCYP3A4ALDH1A1
SCHEMBL10770976 0.80 TTR (0.56) TTRTSHRTPMTSRD5A2ALDH1A1
SCHEMBL1614866 0.79 AKR1C4 (0.65) TSHRTPMTCYP3A4SRD5A2ALDH1A1
SCHEMBL27610170 0.78 TTR (0.54) TTRTSHRTPMTSRD5A2ALDH1A1
SCHEMBL11679297 0.78 TTR (0.54) TTRTSHRTPMTSRD5A2ALDH1A1
SCHEMBL28675233 0.78 CYP3A4 (0.68) TTRTSHRTPMTCYP3A4ALDH1A1
SCHEMBL8779295 0.78 TTR (0.54) TTRTSHRTPMTCYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4042571-A Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant TEIJIN LIMITED (JA) 1977-08-16 US claimed
US-11372330-B2 Anti-reflective coating forming composition containing reaction product of isocyanuric acid compound with benzoic acid compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2022-06-28 US disclosed
US-7846638-B2 Composition for forming anti-reflective coating for use in lithography NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-12-07 US disclosed
EP-1560070-B1 COMPOSITION FOR FORMING ANTIREFLECTION FILM FOR LITHOGRAPHY NISSAN CHEMICAL IND LTD (JP) 2009-12-30 EP disclosed
US-20090117493-A1 Anti-Reflective Coating Forming Composition Containing Reaction Product of Isocyanuric Acid Compound with Benzoic Acid Compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-05-07 US disclosed
US-7425399-B2 Composition for forming anti-reflective coating for use in lithography NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2008-09-16 US disclosed
US-20080206680-A1 Composition for forming anti-reflective coating for use in lithography NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2008-08-28 US disclosed
EP-1939688-A1 COMPOSITION FOR ANTIREFLECTION FILM FORMATION, COMPRISING PRODUCT OF REACTION BETWEEN ISOCYANURIC ACID COMPOUND AND BENZOIC ACID COMPOUND Nissan Chemical Industries, Ltd. (JP) 2008-07-02 EP disclosed
US-20060290429-A1 Composition form forming anti-reflective coating for use in lithography NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2006-12-28 US disclosed
EP-1560070-A1 COMPOSITION FOR FORMING ANTIREFLECTION FILM FOR LITHOGRAPHY Nissan Chemical Industries, Ltd. (JP) 2005-08-03 EP disclosed
US-4042571-A Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant TEIJIN LIMITED (JA) 1977-08-16 US disclosed