Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682379 | 0.88 | POLB (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30271973 | 0.77 | LMNA (0.43) | S1PR1S1PR3S1PR5POLBSMN1; SMN2 | |
| SCHEMBL28568525 | 0.77 | LMNA (0.43) | S1PR1S1PR3S1PR5POLBSMN1; SMN2 | |
| SCHEMBL31756966 | 0.77 | LMNA (0.43) | S1PR1S1PR3S1PR5POLBSMN1; SMN2 | |
| SCHEMBL29431839 | 0.77 | LMNA (0.43) | S1PR1S1PR3S1PR5POLBSMN1; SMN2 | |
| SCHEMBL11681083 | 0.76 | KDM4E (0.44) | POLB | |
| SCHEMBL25453177 | 0.73 | PSEN1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL18965497 | 0.73 | PSEN1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13910201 | 0.73 | PSEN1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1651679 | 0.72 | POLB (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4015974-A | HERBICIDES, INSECTICIDES, NEMATOCIDES, MITICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-04-05 | — | — | US | disclosed |