Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | FAP | Q12884 | 3/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31756966 | 1.00 | LMNA (0.43) | LMNACA12CA1CA2CA3 | |
| SCHEMBL30271973 | 1.00 | LMNA (0.43) | LMNACA12CA1CA2CA3 | |
| SCHEMBL29431839 | 1.00 | LMNA (0.43) | LMNACA12CA1CA2CA3 | |
| SCHEMBL30381336 | 0.86 | ACE (0.36) | LMNACA12CA1CA2CA3 | |
| SCHEMBL28605644 | 0.86 | ACE (0.36) | LMNACA12CA1CA2CA3 | |
| SCHEMBL23930400 | 0.79 | LMNA (0.46) | LMNACA12CA1CA2CA3 | |
| SCHEMBL20630145 | 0.79 | LMNA (0.46) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11680756 | 0.77 | PSEN1 (0.37) | POLBS1PR1S1PR3S1PR5SMN1; SMN2 | |
| SCHEMBL6977660 | 0.75 | CA1 (0.38) | LMNACA12CA1CA2CA3 | |
| SCHEMBL2026586 | 0.74 | KDM4E (0.46) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118028391-A | Preparation method of S-configuration monoamide compound and brivaracetam intermediate | 北京泛球生物科技有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-111333563-B | Preparation method of buvaracetam intermediate | 上海科胜药物研发有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-111579706-B | Method for detecting hydrolysis impurities of brivaracetam | 宜宾市南溪区红光制药有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-112955430-B | Preparation method of brivaracetam and intermediate thereof | 浙江华海药业股份有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-111154735-B | Preparation method of ketene reductase and brivaracetam intermediate | 宁波酶赛生物工程有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-113582902-A | Preparation method of brivaracetam and intermediate thereof | 浙江华海药业股份有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113024434-A | Preparation method of brivaracetam intermediate | 上海科胜药物研发有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-112955430-A | Preparation method of brivaracetam and intermediate thereof | 浙江华海药业股份有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-111333563-A | Preparation method of brivaracetam intermediate | 上海科胜药物研发有限公司 | 2020-06-26 | — | — | CN | disclosed |
| CN-111154735-A | Preparation method of ketene reductase and brivaracetam intermediate | 宁波酶赛生物工程有限公司 | 2020-05-15 | — | — | CN | disclosed |