Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.68 |
| ▸ | CTSK | P43235 | 8/20 | 0.68 |
| ▸ | CTSB | P07858 | 3/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684424 | 1.00 | CTSS (0.68) | CTSSCTSKCTSBCTSLOPRD1 | |
| SCHEMBL11680386 | 1.00 | CTSS (0.68) | CTSSCTSKCTSBCTSLOPRD1 | |
| SCHEMBL4024908 | 0.89 | CTSS (0.69) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL4024913 | 0.89 | CTSS (0.69) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL3469005 | 0.89 | CTSS (0.69) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL3469003 | 0.89 | CTSS (0.69) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL11681965 | 0.88 | CTSS (0.61) | CTSSCTSKCTSBCTSLOPRD1 | |
| SCHEMBL11124222 | 0.87 | CTSS (0.71) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL11525136 | 0.87 | CTSS (0.64) | CTSSCTSKCTSBCTSLOPRD1 | |
| SCHEMBL11523721 | 0.87 | CTSS (0.64) | CTSSCTSKCTSBCTSLOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4028319-A | 2 AND 3-SUBSTITUTED ENKEPHALINS | G. D. SEARLE & CO. (US) | 1977-06-07 | — | — | US | disclosed |