Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.64 |
| ▸ | CTSK | P43235 | 9/20 | 0.64 |
| ▸ | ACE | P12821 | 1/20 | 0.61 |
| ▸ | CTSB | P07858 | 4/20 | 0.61 |
| ▸ | CTSL | P07711 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.54 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.54 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.54 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523721 | 1.00 | CTSS (0.64) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL11525133 | 1.00 | CTSS (0.64) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL8580174 | 0.92 | REN (0.60) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL11528388 | 0.91 | CTSS (0.61) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL30865868 | 0.91 | CTSS (0.61) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL30100564 | 0.91 | CTSS (0.61) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL236543 | 0.91 | OPRD1 (0.64) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL236544 | 0.91 | OPRD1 (0.64) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL11607639 | 0.89 | CTSS (0.63) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL30100566 | 0.89 | CTSS (0.63) | CTSSCTSKACECTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170290892-A1 | POLYMERIC ENKEPHALIN PRODRUGS | PEG BIOSCIENCES, INC. (US) | 2017-10-12 | — | — | US | disclosed |
| EP-3169406-A1 | POLYMERIC ENKEPHALIN PRODRUGS | PEG Biosciences, Inc. (US) | 2017-05-24 | — | — | EP | disclosed |
| CN-106535944-A | Polymeric enkephalin prodrugs | PEG生物制药公司 | 2017-03-22 | — | — | CN | disclosed |
| WO-2016011037-A1 | POLYMERIC ENKEPHALIN PRODRUGS | PEG BIOSCIENCES, INC. (US) | 2016-01-21 | — | — | WO | disclosed |
| US-4144228-A | Methionine5 -enkephalin sulfoxides and sulfones | G. D. SEARLE & CO. (US) | 1979-03-13 | — | — | US | disclosed |