Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11680934 | 1.00 | MAPT (0.42) | MAPTMIFALDH1A1USP2ALOX15 | |
| SCHEMBL11747683 | 1.00 | MAPT (0.42) | MAPTMIFALDH1A1USP2ALOX15 | |
| SCHEMBL25648750 | 0.98 | MAPT (0.44) | MAPTMIFALDH1A1USP2ALOX15 | |
| SCHEMBL29084231 | 0.98 | MAPT (0.44) | MAPTMIFALDH1A1USP2ALOX15 | |
| SCHEMBL472121 | 0.98 | MAPT (0.44) | MAPTMIFALDH1A1USP2ALOX15 | |
| SCHEMBL34475901 | 0.89 | MAPT (0.51) | MAPTALDH1A1USP2ALOX15TDP1 | |
| SCHEMBL16085913 | 0.86 | ALDH1A1 (0.49) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL16085912 | 0.86 | ALDH1A1 (0.49) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL2586974 | 0.85 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4754792 | 0.84 | PPM1B (0.41) | MAPTMIFALDH1A1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048214-A | Production of alicyclic unsaturated compounds having pendent functional groups | STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) | 1977-09-13 | — | — | US | claimed |
| US-4056552-A | Ethyl 3,7-cyclodecadiene-1-carboxylate | STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) | 1977-11-01 | — | — | US | disclosed |