Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.53 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.45 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.45 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 6/20 | 0.41 |
| ▸ | CTSD | P07339 | 2/20 | 0.41 |
| ▸ | CTSE | P14091 | 2/20 | 0.41 |
| ▸ | PGC | P20142 | 2/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11685174 | 0.98 | GBA1 (0.51) | GBA1SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL8035229 | 0.81 | GBA1 (0.48) | GBA1 | |
| SCHEMBL4709103 | 0.80 | GBA1 (0.53) | GBA1RENCTSDCTSEPGC | |
| SCHEMBL6001919 | 0.78 | GBA1 (0.68) | GBA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5974321 | 0.78 | GBA1 (0.68) | GBA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5973809 | 0.78 | GBA1 (0.68) | GBA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5205480 | 0.78 | GBA1 (0.68) | GBA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7226927 | 0.78 | GBA1 (0.68) | GBA1RENCTSDCTSEPGC | |
| SCHEMBL6001914 | 0.78 | GBA1 (0.68) | GBA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11883450 | 0.78 | SLC6A11 (0.50) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4034095-A | ANTIDEPRESSANT, ANTICHOLINERGIC | SANDOZ LTD. (CH) | 1977-07-05 | — | — | US | disclosed |
| US-4024265-A | ANTIDEPRESSANTS | SANDOZ LTD. (CH) | 1977-05-17 | — | — | US | disclosed |