Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28494730 | 0.82 | PKM (0.60) | GBA1MAPTPKM | |
| SCHEMBL11680968 | 0.81 | GBA1 (0.53) | GBA1 | |
| Hydrochloric Acid SCHEMBL11685174 | 0.79 | GBA1 (0.51) | GBA1MAPTPKM | |
| SCHEMBL7806051 | 0.78 | ALDH1A1 (0.41) | — | |
| SCHEMBL7006297 | 0.76 | GBA1 (0.53) | GBA1 | |
| SCHEMBL5205480 | 0.76 | GBA1 (0.68) | GBA1 | |
| SCHEMBL6001919 | 0.76 | GBA1 (0.68) | GBA1 | |
| SCHEMBL5973809 | 0.76 | GBA1 (0.68) | GBA1 | |
| SCHEMBL5974321 | 0.76 | GBA1 (0.68) | GBA1 | |
| SCHEMBL7242431 | 0.76 | GBA1 (0.53) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |