Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39409 | 0.85 | CNR1 (0.50) | CNR1TACR1PTGS1PTGS2MGLL | |
| SCHEMBL5584090 | 0.85 | CNR1 (0.50) | CNR1TACR1PTGS1PTGS2MGLL | |
| SCHEMBL2893463 | 0.85 | CNR1 (0.50) | CNR1TACR1PTGS1PTGS2MGLL | |
| SCHEMBL5584007 | 0.85 | CNR1 (0.50) | CNR1TACR1PTGS1PTGS2MGLL | |
| SCHEMBL6017344 | 0.83 | TACR1 (0.47) | CNR1TACR1PTGS1PTGS2MGLL | |
| SCHEMBL5605674 | 0.82 | TACR1 (0.46) | CNR1TACR1PTGS1PTGS2MGLL | |
| SCHEMBL11353453 | 0.80 | CNR1 (0.43) | CNR1TACR1PTGS1PTGS2MGLL | |
| SCHEMBL6030261 | 0.79 | CNR1 (0.50) | CNR1TACR1PTGS1PTGS2MGLL | |
| SCHEMBL11153550 | 0.79 | CNR1 (0.48) | CNR1TACR1MGLLFAAHALDH1A1 | |
| SCHEMBL11091144 | 0.78 | CNR1 (0.49) | CNR1TACR1PTGS1PTGS2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052351-A | NICKEL CARBOXYLATE, PIPERIDINE DERIVATIVE | PHILLIPS PETROLEUM COMPANY (US) | 1977-10-04 | — | — | US | disclosed |