Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5605674 | 0.99 | TACR1 (0.46) | TACR1CNR1LMNAPOLBPTGS1 | |
| SCHEMBL5584090 | 0.89 | CNR1 (0.50) | TACR1CNR1PTGS1PTGS2MGLL | |
| SCHEMBL39409 | 0.89 | CNR1 (0.50) | TACR1CNR1PTGS1PTGS2MGLL | |
| SCHEMBL2893463 | 0.89 | CNR1 (0.50) | TACR1CNR1PTGS1PTGS2MGLL | |
| SCHEMBL5584007 | 0.89 | CNR1 (0.50) | TACR1CNR1PTGS1PTGS2MGLL | |
| SCHEMBL11353453 | 0.85 | CNR1 (0.43) | TACR1CNR1LMNAPTGS1PTGS2 | |
| SCHEMBL11153550 | 0.83 | CNR1 (0.48) | TACR1CNR1LMNAMGLLFAAH | |
| SCHEMBL11681007 | 0.83 | CNR1 (0.45) | TACR1CNR1PTGS1PTGS2MGLL | |
| SCHEMBL6017697 | 0.79 | TACR1 (0.45) | TACR1CNR1LMNAKMT2AALDH1A1 | |
| SCHEMBL6030261 | 0.78 | CNR1 (0.50) | TACR1CNR1PTGS1PTGS2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680458-A2 | ROMP WITH FLUORINATED GROUPS | Ciba SC Holding AG (CH) | 2006-07-19 | — | — | EP | disclosed |
| EP-1539873-A2 | STABILLIZATION OF ORGANIC MATERIALS | Ciba SC Holding AG (CH) | 2005-06-15 | — | — | EP | disclosed |
| WO-2005028402-A2 | ROMP WITH FLUORINATED GROUPS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-03-31 | — | — | WO | disclosed |
| WO-2004024810-A2 | STABILLIZATION OF ORGANIC MATERIALS | CIBA, SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-03-25 | — | — | WO | disclosed |