SCHEMBL11091144

SCHEMBL11091144

CCCCCCCCN1C(=O)NC2(CC(C)(C)N(C)C(C)(C)C2)C1=O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.49
TACR1 P25103 1/20 0.46
PTGS1 P23219 3/20 0.44
PTGS2 P35354 3/20 0.44
MGLL Q99685 2/20 0.44
FAAH O00519 2/20 0.44
ALDH1A1 P00352 1/20 0.39
CYP19A1 P11511 7/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11155430 0.94 CNR1 (0.47) CNR1TACR1FAAHALDH1A1CYP19A1
SCHEMBL11482548 0.94 ALDH1A1 (0.43) CNR1TACR1ALDH1A1
SCHEMBL11484816 0.90 CNR1 (0.48) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL11488928 0.90 CNR1 (0.48) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL7699126 0.90 CNR1 (0.48) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL11490607 0.89 CNR1 (0.47) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL11476370 0.89 CNR1 (0.47) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL7511083 0.89 CNR1 (0.47) CNR1TACR1PTGS1PTGS2MGLL
SCHEMBL13613400 0.88 LMNA (0.37) CNR1TACR1ALDH1A1CYP19A1
SCHEMBL5584007 0.87 CNR1 (0.50) CNR1TACR1PTGS1PTGS2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3941744-A SYNTHETIC RESIN SANKYO COMPANY LIMITED (JA) 1976-03-02 US claimed
US-4426471-A TETRAALKYLPIPERIDINES CIBA-GEIGY CORPORATION (US) 1984-01-17 US disclosed
US-4396735-A N-HETEROCYCLIC COMPOUND AND A HETEROCYCLIC ACID HYDRAZIDE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-08-02 US disclosed
US-4362831-A A HINDERED AND HETEROCYCLIC AMINE WITH A THIOALKANOIC ACID AMIDE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-12-07 US disclosed
US-4241208-A STABILIZERS OF SYNTHETIC POLYMERS AGAINST HEAT AND LIGHT SANKYO COMPANY LIMITED (JP) 1980-12-23 US disclosed
US-4066615-A PHOTOSTABILITY, THERMAL STABILITY SANKYO COMPANY LIMITED (JA) 1978-01-03 US disclosed
US-3941744-A SYNTHETIC RESIN SANKYO COMPANY LIMITED (JA) 1976-03-02 US disclosed