Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.79 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.79 |
| ▸ | PGR | P06401 | 5/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.79 |
| ▸ | AR | P10275 | 3/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682137 | 0.94 | CYP3A4 (0.77) | CYP3A4NR3C1PGRHIF1AAR | |
| SCHEMBL11680830 | 0.93 | CYP3A4 (0.78) | CYP3A4NR3C1PGRHIF1AAR | |
| SCHEMBL11683285 | 0.91 | CYP3A4 (0.66) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL13769220 | 0.88 | CYP3A4 (1.00) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL21111542 | 0.88 | CYP3A4 (1.00) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL4694 | 0.88 | CYP3A4 (1.00) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL5042122 | 0.88 | CYP3A4 (1.00) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL13423594 | 0.88 | CYP3A4 (1.00) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL5490827 | 0.88 | CYP3A4 (1.00) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL3692151 | 0.87 | CYP3A4 (0.97) | CYP3A4NR3C1PGRHIF1AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065452-A | TOPICAL ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-12-27 | — | — | US | disclosed |