SCHEMBL11682002

SCHEMBL11682002

O=C(O)Cc1ccc(N2C=NCC2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 1/20 0.50
NSD2 O96028 1/20 0.47
POLB P06746 1/20 0.47
GRK2 P25098 1/20 0.47
CASP6 P55212 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
KLKB1 P03952 1/20 0.46
CTSB P07858 1/20 0.46
ITGB3 P05106 4/20 0.46
ITGA2B P08514 4/20 0.46
LMNA P02545 2/20 0.43
CA2 P00918 1/20 0.43
CAMK2A Q9UQM7 1/20 0.43
AKR1B1 P15121 1/20 0.41
ABCC4 O15439 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
PTGS1 P23219 1/20 0.41
HTT P42858 1/20 0.41
TBXAS1 P24557 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11712331 0.98 QPCT (0.49) QPCTNSD2POLBGRK2CASP6
Hydrochloric Acid SCHEMBL11681523 0.84 QPCT (0.34) QPCTNSD2POLBGRK2CASP6
SCHEMBL11681224 0.77 NR4A1 (0.50) ITGB3ITGA2BTSHRTBXAS1ALDH1A1
Hydrochloric Acid SCHEMBL11715333 0.76 NR4A1 (0.49) ITGB3ITGA2BTSHRTBXAS1ALDH1A1
SCHEMBL1065084 0.70 ITGB3 (0.64) QPCTNSD2POLBGRK2CASP6
SCHEMBL2285282 0.70 ITGB3 (0.64) QPCTNSD2POLBGRK2CASP6
SCHEMBL24059106 0.70 ITGB3 (0.58) QPCTNSD2POLBGRK2CASP6
SCHEMBL69614 0.70 CA2 (0.79) QPCTNSD2POLBGRK2CASP6
SCHEMBL13855699 0.69 ITGB3 (0.62) QPCTNSD2POLBGRK2CASP6
SCHEMBL2282564 0.69 ITGB3 (0.62) QPCTNSD2POLBGRK2CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4018933-A PENICILLINS; BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DT) 1977-04-19 US disclosed
US-4016159-A BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed