Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27352539 | 0.82 | CA1 (0.43) | LMNACA1CA2TSHRCHRM1 | |
| SCHEMBL7620669 | 0.75 | CA1 (0.35) | LMNACA1CA2TSHRMETAP1 | |
| SCHEMBL7620410 | 0.73 | CA1 (0.34) | LMNACA1CA2TSHRMETAP1 | |
| SCHEMBL7622190 | 0.73 | CA1 (0.34) | LMNACA1CA2TSHRMETAP1 | |
| SCHEMBL7629340 | 0.73 | CA1 (0.34) | LMNACA1CA2TSHRMETAP1 | |
| SCHEMBL9080365 | 0.73 | TSHR (0.35) | LMNACA1CA2TSHRTDP1 | |
| SCHEMBL27522290 | 0.73 | CA1 (0.39) | LMNACA1CA2TSHR | |
| SCHEMBL21609358 | 0.73 | SLC7A5 (0.34) | CA1CA2TSHRADRA1A | |
| SCHEMBL7624156 | 0.72 | LMNA (0.44) | LMNACA1CA2 | |
| SCHEMBL7623699 | 0.72 | LMNA (0.44) | LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054569-A | CNS DEPRESSANTS, ANTICONVULSIVES, ANTIINFLAMMATORY | AYERST MCKENNA & HARRISON LTD. (CA) | 1977-10-18 | — | — | US | disclosed |
| US-3985751-A | CNS DEPRESSANTS, ANTICONVULSANT AND ANTIINFLAMMATORY AGENTS | AYERST MCKENNA AND HARRISON LTD. (CA) | 1976-10-12 | — | — | US | disclosed |