Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620410 | 1.00 | CA1 (0.34) | CA1CA2ALDH1A1EPHX1LMNA | |
| SCHEMBL7622190 | 1.00 | CA1 (0.34) | CA1CA2ALDH1A1EPHX1LMNA | |
| SCHEMBL7620669 | 0.98 | CA1 (0.35) | CA1CA2ALDH1A1EPHX1LMNA | |
| SCHEMBL7620552 | 0.92 | CA2 (0.41) | CA1CA2EPHX1LMNACYP2D6 | |
| SCHEMBL7618418 | 0.92 | CA2 (0.41) | CA1CA2EPHX1LMNACYP2D6 | |
| SCHEMBL7623724 | 0.92 | CA2 (0.41) | CA1CA2EPHX1LMNACYP2D6 | |
| SCHEMBL7621633 | 0.92 | CA2 (0.41) | CA1CA2EPHX1LMNACYP2D6 | |
| SCHEMBL7624156 | 0.90 | LMNA (0.44) | CA1CA2EPHX1LMNACYP2D6 | |
| SCHEMBL7623699 | 0.90 | LMNA (0.44) | CA1CA2EPHX1LMNACYP2D6 | |
| SCHEMBL7617672 | 0.90 | LMNA (0.44) | CA1CA2EPHX1LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444832-B1 | OSTEOPOROSIS | ESSWEIN ANGELIKA (DE) | 2002-09-03 | — | — | US | disclosed |
| EP-0865422-B1 | USE OF AMINOALCOHOLDERIVATIVES AS DRUGS, DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ROCHE DIAGNOSTICS GMBH (DE) | 2001-07-11 | — | — | EP | disclosed |