Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | SLC7A11 | Q9UPY5 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685529 | 0.87 | POLB (0.43) | POLBL3MBTL1MEN1KMT2ARXFP1 | |
| SCHEMBL11680641 | 0.84 | CYP2C9 (0.48) | POLBL3MBTL1MEN1KMT2ARXFP1 | |
| SCHEMBL11682813 | 0.84 | POLB (0.41) | POLBL3MBTL1MEN1KMT2ARXFP1 | |
| SCHEMBL8769337 | 0.80 | POLB (0.56) | POLBL3MBTL1MEN1KMT2ARXFP1 | |
| 3-Chloroaniline SCHEMBL11686685 | 0.76 | SMN1; SMN2 (0.39) | POLBL3MBTL1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6152252 | 0.75 | SMN1; SMN2 (0.53) | POLBL3MBTL1MEN1KMT2ARXFP1 | |
| Aniline SCHEMBL11683907 | 0.74 | CYP2D6 (0.54) | POLBMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2120389 | 0.73 | RAPGEF4 (0.49) | POLBL3MBTL1MEN1KMT2ARXFP1 | |
| SCHEMBL11771164 | 0.73 | POLB (0.50) | POLBL3MBTL1MEN1KMT2ARXFP1 | |
| Aniline SCHEMBL11682873 | 0.73 | TSHR (0.56) | POLBKMT2ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |