SCHEMBL8769337

SCHEMBL8769337

Nc1ccc(Oc2ccccc2)c(S(=O)(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
RXFP1 Q9HBX9 2/20 0.56
APEX1 P27695 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.52
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
MAPT P10636 2/20 0.51
NSD2 O96028 1/20 0.51
GAA P10253 1/20 0.51
APOBEC3A P31941 1/20 0.51
RECQL P46063 1/20 0.51
CASP6 P55212 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 1/20 0.46
DUSP3 P51452 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2120389 0.90 RAPGEF4 (0.49) POLBL3MBTL1RXFP1APEX1MEN1
Ammonia Solution, Strong SCHEMBL7555706 0.89 RAPGEF4 (0.47) POLBL3MBTL1RXFP1APEX1MEN1
SCHEMBL1259167 0.87 POLB (0.44) POLBL3MBTL1RXFP1APEX1MEN1
SCHEMBL487024 0.86 RAPGEF4 (0.50) POLBL3MBTL1RXFP1APEX1MEN1
SCHEMBL31184477 0.86 RAPGEF4 (0.50) POLBL3MBTL1RXFP1APEX1MEN1
Ammonia Solution, Strong SCHEMBL7550375 0.84 RAPGEF4 (0.49) POLBL3MBTL1RXFP1APEX1MEN1
Trimethylammonium SCHEMBL7550916 0.84 POLB (0.45) POLBL3MBTL1RXFP1APEX1MEN1
SCHEMBL11659131 0.84 KMT2A (0.49) POLBL3MBTL1RXFP1APEX1MEN1
SCHEMBL29625906 0.84 BRD4 (0.46) POLBL3MBTL1RXFP1APEX1MEN1
SCHEMBL28738313 0.84 BRD4 (0.46) POLBL3MBTL1RXFP1APEX1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0568892-B1 Monoazo reactive dyes BAYER AG (DE) 1997-09-17 EP disclosed
EP-0482789-B1 Benzoquinone compounds ZENECA LTD (GB) 1996-01-03 EP disclosed
US-5391716-A Monoazo 2-hydroxy-pyridone-containing reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1995-02-21 US disclosed
EP-0356014-B1 Reactive Dyes ZENECA LTD (GB) 1994-11-30 EP disclosed
EP-0377189-B1 Reactive dyes BAYER AG (DE) 1994-09-07 EP disclosed
US-5283355-A Benzoquinone compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-02-01 US disclosed
EP-0568892-A2 Monoazo reactive dyes BAYER AG (DE) 1993-11-10 EP disclosed
EP-0482789-A2 Benzoquinone compounds ZENECA LIMITED (GB) 1992-04-29 EP disclosed
US-5093482-A REACTIVE DYESTUFFS BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed
EP-0299328-B1 REACTIVE DYES BAYER AG (DE) 1991-07-10 EP disclosed
EP-0377189-A1 Reactive dyes BAYER AG (DE) 1990-07-11 EP disclosed
EP-0356014-A1 Reactive Dyes ZENECA LIMITED (GB) 1990-02-28 EP disclosed
US-4851527-A Water-soluble triphendioxazine compounds HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-25 US disclosed
EP-0299328-A2 Reactive dyes BAYER AG (DE) 1989-01-18 EP disclosed
EP-0140252-B1 POLYAZO DYES BASF Aktiengesellschaft (DE) 1988-01-07 EP disclosed
EP-0212635-A1 Water soluble triphenedioxazine compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-04 EP disclosed
EP-0212412-A2 Polyazo dyes BAYER AG (DE) 1987-03-04 EP disclosed
US-4563520-A COLORFAST BROWN SYEINGS ON LEATHER BASF AKTIENGESELLSCHAFT (DE) 1986-01-07 US disclosed
US-4491543-A BROWN DYES ON LEATHER BASF AKTIENGESELLSCHAFT (DE) 1985-01-01 US disclosed
EP-0078007-A1 Metallised polyazo dyestuffs BASF Aktiengesellschaft (DE) 1983-05-04 EP disclosed