Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.71 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCND3 | P30281 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685205 | 0.83 | MAP2K4 (0.50) | IDO1MAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL31677101 | 0.79 | ALDH1A1 (0.62) | IDO1MAPK14ALDH1A1MAPTHPGD | |
| SCHEMBL11682988 | 0.79 | ALDH1A1 (0.62) | IDO1MAPK14ALDH1A1MAPTHPGD | |
| SCHEMBL11683287 | 0.77 | CDK2 (0.63) | IDO1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL11686488 | 0.77 | MAP2K4 (0.63) | IDO1MAPK14ALDH1A1HPGDCDK2 | |
| SCHEMBL11685176 | 0.77 | MAP2K4 (0.55) | IDO1ALDH1A1HPGDCDK2CDK4 | |
| SCHEMBL17829918 | 0.76 | IDO1 (0.65) | IDO1ALDH1A1MAPTHPGDHTT | |
| SCHEMBL11682161 | 0.76 | MKNK1 (0.63) | IDO1ALDH1A1HPGDCDK2CDK4 | |
| SCHEMBL11687075 | 0.74 | KMT2A (0.54) | MAPK14MAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL11683985 | 0.74 | PDE4A (0.62) | MAPK14ALDH1A1HPGDCDK2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042704-A | FERTILITY CONTROL AGENTS | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | disclosed |