SCHEMBL11683046

SCHEMBL11683046

CC(O)c1ccc(/C=C/C(=O)O)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.76
MAPK1 P28482 3/20 0.76
CA12 O43570 3/20 0.57
CA1 P00915 3/20 0.57
CA2 P00918 3/20 0.57
CA3 P07451 3/20 0.57
CA4 P22748 3/20 0.57
CA6 P23280 3/20 0.57
CA5A P35218 3/20 0.57
CA7 P43166 3/20 0.57
CA9 Q16790 3/20 0.57
CA14 Q9ULX7 3/20 0.57
CA5B Q9Y2D0 3/20 0.57
HCAR2 Q8TDS4 2/20 0.57
AKR1B10 O60218 2/20 0.57
AKR1B1 P15121 2/20 0.57
DPP4 P27487 2/20 0.57
ESR1 P03372 2/20 0.57
ESR2 Q92731 2/20 0.57
PKM P14618 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1711780 0.86 KDM4E (1.00) KDM4EMAPK1CA12CA1CA2
SCHEMBL819055 0.86 KDM4E (1.00) KDM4EMAPK1CA12CA1CA2
SCHEMBL13476341 0.85 TDP1 (0.57) KDM4EMAPK1CA12CA1CA2
SCHEMBL10898086 0.84 KDM4E (0.69) KDM4EMAPK1CA12CA1CA2
SCHEMBL12814412 0.83 KDM4E (0.73) KDM4EMAPK1CA12CA1CA2
SCHEMBL28002416 0.83 KDM4E (0.73) KDM4EMAPK1CA12CA1CA2
SCHEMBL4322158 0.83 KDM4E (0.73) KDM4EMAPK1CA12CA1CA2
SCHEMBL7140088 0.83 KDM4E (0.73) KDM4EMAPK1CA12CA1CA2
SCHEMBL28098346 0.83 KDM4E (0.53) KDM4EMAPK1CA12CA1CA2
SCHEMBL3156394 0.81 KDM4E (0.71) KDM4EMAPK1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4053415-A UNSATURATED POLYESTER ETHER HAVING A PHOTOCROSSLINKABLE MOIETY FUJI PHOTO FILM CO., LTD. (JA) 1977-10-11 US disclosed