Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.73 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | DPP4 | P27487 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140088 | 1.00 | KDM4E (0.73) | KDM4EMAPK1HCAR2CA12AKR1B10 | |
| SCHEMBL819055 | 0.85 | KDM4E (1.00) | KDM4EMAPK1HCAR2CA12AKR1B10 | |
| SCHEMBL1711780 | 0.85 | KDM4E (1.00) | KDM4EMAPK1HCAR2CA12AKR1B10 | |
| SCHEMBL11683046 | 0.83 | KDM4E (0.76) | KDM4EMAPK1HCAR2CA12AKR1B10 | |
| SCHEMBL28002416 | 0.81 | KDM4E (0.73) | KDM4EMAPK1HCAR2CA12AKR1B10 | |
| SCHEMBL12814412 | 0.81 | KDM4E (0.73) | KDM4EMAPK1HCAR2CA12AKR1B10 | |
| SCHEMBL28948630 | 0.81 | CA12 (0.62) | KDM4EMAPK1CA12AKR1B10CA1 | |
| SCHEMBL3156394 | 0.80 | KDM4E (0.71) | KDM4EMAPK1HCAR2CA12AKR1B10 | |
| SCHEMBL713717 | 0.79 | HCAR2 (0.81) | KDM4EMAPK1HCAR2CA12AKR1B10 | |
| SCHEMBL68395 | 0.79 | HCAR2 (0.81) | KDM4EMAPK1HCAR2CA12AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104371071-A | Preparation method for hyperbranched polycarboxylic-acid concrete efficient water reducer | JIANGSU SUBOTE NEW MAT CO LTD | 2015-02-25 | — | — | CN | disclosed |
| WO-2009144201-A1 | IMIDAZOPYRIDINE DERIVATIVES AS GPR4 RECEPTOR MODULATORS | NOVARTIS AG (CH) | 2009-12-03 | — | — | WO | disclosed |
| US-20090291942-A1 | IMIDAZO PYRIDINE DERIVATIVES | TARACIDO IVAN CORNELLA | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291942-A1 | IMIDAZO PYRIDINE DERIVATIVES | FLT4, UACA, FLT1 | KDM4E 1742/4885MAPK1 872/4885HCAR2 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.